Cyclic substituted ureas having a physiological cooling effect

Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof

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424272, 131 17R, 131202, 252110, 252522, 260239B, 260239F, 260307FA, 2603264, 544 88, 544 96, 544130, 544141, 544165, 544168, 544 63, 424 45, 424 48, 424 64, 424 69, 424 70, 424 73, 424244, 42424854, 42424856, 42424857, 424267, 424274, 426590, 426660, A61K 722

Patent

active

041373049

ABSTRACT:
Cyclic and acyclic amides, substituted ureas and sulphonamides are disclosed having the property of stimulating the cold receptors of the nervous system of the body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.

REFERENCES:
patent: 2640055 (1953-05-01), King et al.
patent: 2857430 (1958-10-01), Applegath et al.
patent: 4044120 (1977-08-01), Rowsell et al.

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