Neuroprotective drug

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31425

Patent

active

053995716

ABSTRACT:
A neuroprotecting drug comprises as an essential active ingredient ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]pyrrol-1-yl acetate, which is useful with high safety for the prophylaxis and treatment of brain dysfunction induced by hypoxia due to the disturbance of cerebral circulation such as cerebral hemorrhage or cerebral infarction in human being.

REFERENCES:
patent: 4168315 (1979-09-01), Rynbrandt et al.
patent: 4659726 (1987-04-01), Yoshino et al.
Seminars in Neurology, vol. 11, No. 4, Dec. 1991, pp. 353-367, J. Biller et al. `Antithrombotic therapy for ischemic cerebrovascular disease`.
Dialog Information Services, File 55, Accession No. 9325804 & JPN J Pharmacol (Suppl. 1), vol. 59, 1992, p. 346P, N. Yamamoto et al., `Protective effect of KBT-3022 a new anti-platelet agent in experimental cerebral ischemic models`.

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