Intracellular temperature measurement

Details Intracellular temperature measurement Intracellular temperature measurement

1977-03-09

1979-01-30

Howell, Kyle L.

Surgery

Truss

Perineal

128 13, A61B 505

Patent

active

041366832

ABSTRACT:
The process comprises introducing minute particles into the interior of the cells. These particles being injected intraveneously while suspended in an appropriate solution are of the size generally having a diameter of approximately 1 micron or less and are of a material with properties such as ferromagnetic, paramagnetic, or diamagnetic. Shortly after being absorbed intracellularly, these particles will assume the same temperature as the respective cells which they have entered. It is a well established principle that the magnetic characteristics of ferromagnetic, paramagnetic, and diamagnetic materials vary as a function of their temperature. By measuring the magnetic characteristics of these particles shortly after they have entered the cell and with proper calibration, an exact determination of the temperature of the particle and therefore of the cell, can be made.

REFERENCES:
patent: 3712291 (1973-01-01), Freeman
patent: 3789834 (1974-02-01), Duroux
patent: 3877463 (1975-04-01), Cary et al.
Newbower, R. S., IEEE Trans. on Magnetics, vol. Mag-9, No. 3, pp. 447-450, Sep. 1973.
Kaiser et al., IEEE Trans. on Magnetics, vol. Mag.-6, No. 3, pp. 694-698, Sep. 1970.
Gillespie, P. J. et al., Bio-Med. Engng., vol. 6, No. 8, pp. 358-362, Aug. 1971.

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