Methods for inhibiting the proliferation of brain and hepatic me

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514700, 424 10, A61K 31415, A61K 3111

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active

052603270

ABSTRACT:
This invention provides methods for inhibiting the proliferation of brain or hepatic metastases, in vivo, by contacting the cells with lonidamine and radiation.

REFERENCES:
Field, J. B., et al., Cancer Res., 24(1):40-42, 57 (1964).
Kim, J. H., et al., Cancer Res., 46:1120-1123 (1986).
Kim, J. H. et al.: Clinical Study of the Sequence of Combined Hyperthermia and Radiation Therapy of Malignant Melanoma. In Hyperthermic Oncology, vol. 1, J. Overgaard (Ed.), London, Philadelphia; Taylor and Francis, 1984, pp. 387-390.

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