Fused benzeneoxyacetic acid derivatives which have PGI.sub.2 rec

Details Fused benzeneoxyacetic acid derivatives which have PGI.sub.2 rec Fused benzeneoxyacetic acid derivatives which have PGI.sub.2 rec

1994-11-03

1996-12-31

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548215, C07D26102, A61K 3142

Patent

active

055894968

ABSTRACT:
A fused benzeneoxyacetic acid derivative of the formula (I): ##STR1## where the substituents are defined in the specification and salts thereof possess an agonistic on PGI.sub.2 receptor, so it is useful for prevention and/or treatment of thrombosis, arteriosclerosis, inchemic heart diseases, gastric alcer and hypertension.

REFERENCES:
patent: 4349684 (1982-09-01), Lautenschalger et al.
patent: 4367235 (1983-01-01), Ross et al.
patent: 4492708 (1985-01-01), Spitzer
patent: 4956379 (1990-09-01), Meanwell
patent: 5011851 (1991-04-01), Meanwell
patent: 5389666 (1995-02-01), Hamanaka et al.
Nature, vol., 263, Oct. 21, 1976, pp. 663-665.
Prostaglandins, vol. 12, No. 5, Nov. 1976, pp. 685-713.
Prostaglandins, vol. 12, No. 6, Dec. 1976, pp. 915-928.
Prostaglandins, vol. 13, No. 3, Mar. 1977, pp. 375-388.
Chemical & Engineering News, Dec. 20, 1976, pp. 17-19.
Br. J. Pharmac. 76, 1982, pp. 423-438.
Br. J. Pharmac. 84, 1985 pp. 595-607.
Br. J. Pharmac. 102, 1991, pp. 251-259.
Br. J. Pharmac. 102, 1991, pp. 260-265.

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