Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing
Patent
1992-05-26
1995-05-02
Richter, Johann
Organic compounds -- part of the class 532-570 series
Organic compounds
Silicon containing
556440, 556441, 556443, 556446, 556449, 556465, 560 55, 560 61, 560 84, 560 85, 560106, 560107, 560185, 560186, 560187, 560188, 568644, 568660, 568839, C07D47318
Patent
active
054121345
ABSTRACT:
The protected cyclobutanone of the formula ##STR1## is treated with a dialkylaluminum chloride, an alkylaluminum dichloride, a trialkylaluminum compound, diphenylsilane in the presence of tris(triphenylphosphine) rhodium (I) chloride, or iridium tetrachloride to yield the corresponding diprotected cyclobutanol. This compound is useful as an intermediate in the preparation of antiviral agents.
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patent: 5126345 (1992-06-01), Slusarchyk et al.
patent: 5153352 (1992-10-01), Norbek et al.
patent: 5185463 (1993-02-01), Godfrey et al.
Fieser et al., "Reagents For Organic Synthesis", vol. 2, 1972, p. 228.
Fieser et al., "Reagents For Organic Synthesis", vol. 9, 1981, p. 486.
Fieser, et al., "Reagents For Organic Synthesis", vol. 6, 1977, p. 307.
Hasek et al, Research, 14:74-76 (1961), "Derivatives of Dimethylketene".
Bisacchi Gregory S.
Mueller Richard H.
Singh Janak
Davis Stephen B.
E. R. Squibb & Sons Inc.
Peabody John
Richter Johann
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