Process for the preparation of substituted 2,3-difluoropyridines

Details Process for the preparation of substituted 2,3-difluoropyridines Process for the preparation of substituted 2,3-difluoropyridines

Filed on

1993-02-18

Date issued

1995-11-21

Examiner

Ivy, C. Warren

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

546286, 546287, C07D21138

Type

Patent

Status

active

Patent number

054688639

Description

ABSTRACT:
The invention relates to a novel process for the preparation of substituted 2,3-difluoropyridines by reaction of substituted 2,3-halopyridines with fluoride salts in the presence of phase transfer catalysts, preferably in polar aprotic solvents, without removing the resulting substituted 2,3-difluoropyridines continuously from the reaction mixture. The substituted 2,3-difluoropyridines which can be prepared according to the invention are, inter alia, starting materials for the preparation of plant protection agents or pharmaceuticals.

REFERENCES:
patent: 4822887 (1989-04-01), Little et al.
S. Kumai,m et al, Chem. Abs. 117:233865k (1992) JP 04-164068.

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