Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1993-10-15
1995-11-21
Russel, Jeffrey E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
204403, 435 29, 435817, 4352841, 4352865, 4352871, 4352872, C12M 134, C12M 140, C12Q 102, C12Q 125
Patent
active
054686059
ABSTRACT:
One aspect of the invention is the method of operating a microphysiometer including a plunger assembly having a plunger body with a microchamber at one end for receiving a sample and a passage in the plunger body communicating with the microchamber comprises passing a medium transversely through the-sample in the microchamber. Another aspect of the invention is the construction of the plunger assembly wherein the sample is positioned in the microchamber and the passage and microchamber are constructed and arranged so that medium flow is transverse through the sample. The sample may be a tissue slice retained between a pair of screens or membranes, adherent cells on a mesh screen or non-adherent cells retained in a chamber defined by a washer and a pair of screens or membranes.
REFERENCES:
patent: 5104804 (1992-04-01), Humphries et al.
patent: 5206170 (1993-04-01), Sato et al.
patent: 5250419 (1993-10-01), Bernard et al.
patent: 5312762 (1994-05-01), Guiseppi-Elie
patent: 5395503 (1995-03-01), Parce et al.
Science, vol. 246, issued 13 Oct. 1989, Parce et al., "Detection of Cell-Affecting Agents with a Silicon Biosensor", pp. 243-247.
Dawes Timothy D.
Harris Albert K. M.
Kirk Gregory L.
Kuo Richard C.
Owicki John C.
Molecular Devices Corp.
Russel Jeffrey E.
LandOfFree
Transverse flow plungers for microphysiometers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Transverse flow plungers for microphysiometers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transverse flow plungers for microphysiometers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1136103