Methods and materials for improved high gradient magnetic separa

Details Methods and materials for improved high gradient magnetic separa Methods and materials for improved high gradient magnetic separa

1993-02-17

1995-05-02

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 4, 435 5, 435 71, 435 72, 435 792, 4351739, 435174, 435299, 436501, 436526, 536 254, 209 47, 209 49, 209213, 210691, 210695, 252 6254, C12Q 168, G01N 3353, C12M 140

Patent

active

054118638

ABSTRACT:
Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. Superior superparamagnetic particles, optionally coated with a polysaccharide or other, usually organic, materials can be prepared in uniform compositions with homogeneous magnetizations. The coating can conveniently be conjugated to a specific binding moiety complementary to a biological material whose purification or separation is desired. In addition, plastic coated matrices which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS.

REFERENCES:
patent: 3970518 (1976-07-01), Giaever
patent: 4018886 (1977-04-01), Giaever
patent: 4230685 (1980-10-01), Senyei et al.
patent: 4375407 (1983-03-01), Kronick
patent: 4452773 (1984-06-01), Molday
patent: 4554088 (1985-11-01), Whitehead et al.
patent: 4664796 (1987-05-01), Graham et al.
patent: 4738773 (1988-04-01), Muller-Ruchholtz et al.
patent: 4770183 (1988-09-01), Groman et al.
Molday, et al., Nature (1977) 268:437-438.
Kronick, et al., Science (1978) 200:1074-1076.
Widder, et al., J. Pharm. Sci. (1979) 68:79-82.
Molday, et al., FEBS Letters (1984) 170(2):232-238.
Miltenyi, Aufbau eines Magnet-Zellseparationsystems (Dec. 1987), University of Cologne, Germany, pp. 1-101.
Molday et al., J. Immunol. Meth. (1982) vol. 52:353-367.

Affiliated with

Also associated with

Rating

Methods and materials for improved high gradient magnetic separa does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and materials for improved high gradient magnetic separa, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and materials for improved high gradient magnetic separa will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1136056