9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexa

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260333, 2603407, 2603409P, 2603453, 424283, 546269, A61K 3135, A61K 3144, C07D21330, C07D31104

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active

042359139

ABSTRACT:
9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans wherein the substituent is hydrogen, methyl, hydroxymethyl, formyl, carboxy, carbamyl, amino, mono- and di-alkylamino, alkanoylamino, phenalkylsulfonamido or alkylsulfonamido, and the corresponding 9-ketones, all of which are useful as CNS agents, especially as analgesics and tranquilizers,intermediates therefor and processes for their preparation.

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patent: 3901926 (1975-08-01), Winn et al.
Mechoulam et al., Chemical Reviews, vol. 76 (1976) pp. 75-112.
Mechoulam et al., Marijuana, Chemistry, Pharmacology and Clinical Effects, Academic Press, New York (1973) pp. 129-130.
Harradence et al., Chemical Abstracts, vol. 33 (1939) 6841q.

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