Measuring cell for micro-assays, comprising membrane electrodes

Details Measuring cell for micro-assays, comprising membrane electrodes Measuring cell for micro-assays, comprising membrane electrodes

1978-05-16

1980-11-25

Kaplan, G. L.

Chemistry: electrical and wave energy

Processes and products

Vacuum arc discharge coating

204195B, 435288, 435291, 435817, G01N 2730, C12Q 100

Patent

active

042356873

ABSTRACT:
The measuring cell is composed of at least one cavity hollowed in a block of chemically inert material or material made chemically inert at least at the surface. The cavity defines a first cylindrical space whose bottom is, over a reduced part of its diameter, extended by a second space defining the measuring chamber proper, of conical, frustoconical or substantially hemispherical shape. The first cylindrical space is designed to receive a measuring electrode terminated by a magnetic torus and, applied, and if necessary held by means of a ferromagnetic ring, against the latter, a membrane, while inlet and outlet ducts for the liquids to be assayed are formed in the block. The cell is especially useful for micro-assays of biological fluids.

REFERENCES:
patent: 3151052 (1964-09-01), Arthur et al.
patent: 3929605 (1975-12-01), Lubbers et al.
patent: 3997420 (1976-12-01), Buzza
patent: 4017374 (1977-04-01), Aas et al.
R. A. Lienado et al., Anal. Chem., vol. 43, No. 11, pp. 1457-1461, (1971). _
Michel Cordonnier et al., Febs Letters, vol. 59, No. 2, pp. 263-267, (1975). _
Christian Calvot et al., Febs Letters, vol. 59, No. 2, pp. 258-262, (1975). _
Anne-Marie Berjonneau et al., Pathologie-Biologie, vol. 22, No. 6, pp. 497-502, (1974). _
G. C. Guilbault et al., Anal. Chem., vol. 42, No. 14, pp. 1779-1783, (1970). _
S. J. Updike et al., Nature, vol. 214, 986-988, (1967). _
G. G. Guilbault et al., J. Amer. Chem. Soc., vol. 91, 2164, (1969). _

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