In situ sporicidal disinfectant

Details In situ sporicidal disinfectant In situ sporicidal disinfectant

1988-11-07

1990-06-26

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Oxidoreductases

424613, 424614, 424615, 424616, 424669, 424670, 424671, 422 29, A61K 3750, A61K 3340, A61K 3318, A61L 216

Patent

active

049370723

ABSTRACT:
The method comprises forming a sporocide having a defined period of sporocidal activity comprising three components including a peroxide or peroxide generating material, a peroxidase and a salt of iodide which serves as a donor molecule; storing the three components in a nonreacting state to maintain the sporocide in an inactive state and admixing the three components in a aqueous based carrier to cause a catalyzed reaction by said peroxidase for generating free radicals and/or byproducts from the iodide salt (donor molecule) and contacting the surface or object to be sterilized with the activated mixture. The concentration level of the three components can be selected such that an active sporocidal state is maintained for any desired period of time.

REFERENCES:
patent: 2425285 (1947-08-01), Strickler
patent: 3248281 (1966-04-01), Goodenough
patent: 3751562 (1973-02-01), Nichols
patent: 4473550 (1984-09-01), Rosenbaum et al.
patent: 4476108 (1984-10-01), Kessler et al.
patent: 4564519 (1986-01-01), Pellico et al.
patent: 4576817 (1986-03-01), Montgomery et al.
patent: 4588586 (1986-05-01), Kessler et al.
Thomas et al., Antimicrob. Agents Chemo. (6-78), pp. 1000-1005.
Chung et al., cited in Chem. Abstracts, vol. 91:106857d, 1979.

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