Process for preparing 3-phenoxy morphinans

Details Process for preparing 3-phenoxy morphinans Process for preparing 3-phenoxy morphinans

1978-06-12

1980-03-18

Rollins, Alton D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546149, 260559P, C07D21720

Patent

active

041940440

ABSTRACT:
The preparation of 3-phenoxy N-substituted morphinans, useful as analgesics from 1-(p-hydroxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline or cyclohexen-(1)-yl-ethylamine and p-phenoxyphenylacetic acid is described.

REFERENCES:
patent: 3634429 (1972-01-01), Leimgruber et al.
patent: 3707470 (1972-12-01), Sawa
Tomita, J. Pham. Soc. Japan 72, pp. 424-426 (1952). CA 47:6430b (1953).
Chem. Abst. 62 11788g & h (1965), Abst. of Japanese Pat. #30,289 ('64), issued Dec. 25, 1964.
Chem. Abst. 59 10009a-g (1963), Abst. of Japanese Pat. #11,127('62), issued Aug. 5, 1962.

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