Cerebrospinal fluid protein fragments

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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424 12, 23230B, G01N 3316, A61K 4300

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active

042050570

ABSTRACT:
The isolation and use of cerebrospinal fluid myelin encephalitogenic protein (EP) fragments as an indicator of disease activity in multiple sclerosis is disclosed. With the use of a double-antibody radioimmunoassay, it was determined that a portion of EP cross-reacting with residues 43-88 (EP-Pl) appears in the cerebrospinal fluid during periods of exacerbation.

REFERENCES:
Fritz et al., Fed. Proc., vol. 36, No. 3, Mar. 1, 1977, p. 1297.

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