Prolactin receptor gene as a genetic marker for increased litter

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 18, 435 912, 435 9121, 536 231, 536 243, 536 2431, 536 2432, 536 241, 536 242, 536 2433, C12Q 168, C12P 1934, C07H 2102, C07H 2104

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059357843

ABSTRACT:
Disclosed herein are genetic markers for pig litter size, methods for identifying such markers, and methods of screening pigs to determine those more likely to produce larger litters and preferably selecting those pigs for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the pig prolactin receptor gene.

REFERENCES:
patent: 5374526 (1994-12-01), Rothschild et al.
patent: 5550024 (1996-08-01), Rothschild et al.
Stratagene Catalog, pp. 131 and 161, 1995.
Edery et al, "Identification and sequence analysis of a second form of prolactin receptor by molecular cloning of complementary DNA from rabbit mammary gland", Proc. Natl. Acad. Sci. 89:2112-2116, Mar. 1989.
Sommers et al, "minimal homology requirements for PCR primers", Nucleic Acids Res. 17(16):6749, 1989.
Rothschild, et al., "The estrogen receptor locus is associated with a major gene influencing litter size in pigs", Proc. Natl. Acad. Sci. USA 93:201-205 (1996).

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