Somatostatin analogues

Details Somatostatin analogues Somatostatin analogues

1978-04-12

1980-05-27

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

042049903

ABSTRACT:
Polypeptides of the formula: ##STR1## the linear precursors and non-toxic acid addition salts thereof, wherein: R is hydrogen, lower alkanoyl, benzoyl, Ala-Gly-, Gly-Gly-Gly-, Ala-D-Ala- or p-Glu;

REFERENCES:
patent: 4061608 (1977-12-01), Sarantakis
patent: 4062816 (1977-12-01), Shields
patent: 4087390 (1978-05-01), Shields
patent: 4093574 (1978-06-01), Shields
Rivier et al., J. Med. Chem. 18, 123 (1975).
Rivier et al., BBRC 65, 746 (1975).
Brown et al., Metabolism 25, No. 11, Suppl. 1, Nov. (1976).
Rivier et al., Peptides (Apr. 11-17, 1976), pp. 437-443.

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