Coccidiosis poultry vaccine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 4351723, 4358523, 4242711, 4241911, 536 231, 536 253, A61K 39002, C12N 1500, C12P 2102

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057957410

ABSTRACT:
This invention relates to novel Eimeria proteins with immunogenic properties as well as to DNA sequences encoding these proteins. These proteins can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding these proteins can be used for the preparation of a vector vaccine against coccidiosis.

REFERENCES:
patent: 5387414 (1995-02-01), Harwood et al.
patent: 5403581 (1995-04-01), Binger et al.
Lillehoj et al., "Protection Against Eimeria Acervuline Infection Correlates with the T-Cell Response to the Recombinant Surface Merozite Antigen P150,", FASEB J., vol. 2, No. 4, 1988, p. A881.
Lillehoj, H.S., "Immune Response During Coccidiosis in SC and FP Chickens. I. In-Vitro Assessment of T-Cell Proliferation Response to Stage-specific Parasite Antigens," Veterinary Immunology and Immunopathology, vol. 13, No. 4, Dec., 1986, pp. 321-330.
Lillehoj, H.S., "Interaction of Helper T-Cells and Cytotoxic T-Cells is Necessary for Protection Against Eimeria Tenella and E. Maxima Infections in Chickens," Poult. Dis., vol. 70, No. SUP1, 1991, p. 73.
Rose et al., "Immunity to Coccidia in Chickens: Adoptive Transfer with Peripheral Blood Lymphocytes and Spleen Cells," Parasite Immunology, vol. 54, No. 3, May, 1982, pp. 171-185.
Rose et al., "Coccidiosis: Rapid Depletion of Circulatory lymphocytes After Challenge of Immune Chickens with Parasite Antigens," Infection and Immunity, vol. 45, No. 1, Jul. 1984.

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