Process for preparing chiral tetracyclic dopaminergic compounds

Details Process for preparing chiral tetracyclic dopaminergic compounds Process for preparing chiral tetracyclic dopaminergic compounds

1995-06-05

1997-08-19

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 61, 564167, 549 77, 549 75, 549496, C07D21520

Patent

active

056590377

ABSTRACT:
A process for preparing a chiral tetracyclic compound of formula: ##STR1## wherein R is hydrogen or a C.sub.1 -C.sub.6 -alkyl group and Z is oxygen, sulfur or --CH.dbd.CH--, the compounds having uses as dopamine agonists. The process involves reacting a chiral starting material and subsequent chiral intermediates in a series of chirality-preserving synthetic reactions.

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