Amino mercapto substituted acylamino acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548344, 548336, 546190, 546226, 26032612R, 26032625, 2603264, 2601125R, 562426, 562556, 562512, 560 16, 560153, 424267, 424273R, 424274, 424319, C07D23364, C07C10352

Type

Patent

Status

active

Patent number

041549465

Description

ABSTRACT:
New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.

REFERENCES:
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patent: 4064235 (1977-12-01), Yanaihara et al.
patent: 4091024 (1978-05-01), Ondetti
patent: 4105789 (1978-08-01), Ondetti et al.
patent: 4116962 (1978-09-01), Ondetti
Latruffe et al., Biochemie 57, pp. 849-857, (1975).
Huang et al., J.A.C.S. 97, 3858-3859, 1975.
Pettit, Synthetic Peptides, vol. 1, 81-171, 1970.
Schmidt et al., Angew. Chem. Intl. Ed. Eng., vol. 15, 1976, No. 1, p. 42.

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