Derivatives of cephalosporins substituted in 3 position by a thi

Details Derivatives of cephalosporins substituted in 3 position by a thi Derivatives of cephalosporins substituted in 3 position by a thi

1982-11-23

1986-09-02

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540225, 540227, C07D50146, A61K 31545

Patent

active

046096540

ABSTRACT:
The present invention relates to new cephalosporins of general formula ##STR1## in which R.sub.1 =R.sub.2 =CH.sub.3 or R.sub.1 and R.sub.2 together form a 1,3-propylene group, A is H, a cation, an ester or a hemiacetal, and R.sub.3 is a heterocycle comprising five or six atoms including at least one atom in the ring of nitrogen. It also relates to a process for preparing these cephalosporins and to the drugs containing them.

REFERENCES:
patent: 4165430 (1979-08-01), Bradshaw et al.
patent: 4237128 (1980-12-01), Cimarusti et al.
patent: 4315005 (1982-02-01), Ayrs et al.

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