Methods of using .beta.-lactam antibacterial agents

Details Methods of using .beta.-lactam antibacterial agents Methods of using .beta.-lactam antibacterial agents

1985-01-24

1986-09-02

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514201, 540205, 540221, 540301, 540314, 540327, 540331, 540333, 540334, 540337, 540338, 540339, 540341, A61K 3143, A61K 31545

Patent

active

046096523

ABSTRACT:
.beta.-Lactam antibiotics having an .alpha.-formamido substituent on the carbon atom adjacent to the carbonyl group of the .beta.-lactam ring and in particular bicyclic compounds having the partial structure: ##STR1## Intermediates and processes for the preparation of the compounds are further disclosed.

REFERENCES:
patent: 3974150 (1976-08-01), Cook et al.
patent: 4281117 (1981-07-01), Chauvette et al.
P. H. Bentley et al., "Transformations Using Benzyl-6-Isocyanopenicillanate", JCS Perkin I, (1979), pp. 2455-2467.
P. H. Bentley et al., "6.alpha.-Substituted Penicillins", JCS Chem. Comm., (1974), pp. 278-279.

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