Combination of pyrimidine derivatives and calcium antagonists to

Details Combination of pyrimidine derivatives and calcium antagonists to Combination of pyrimidine derivatives and calcium antagonists to

1988-12-08

1991-10-22

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514269, 514275, A61K 31505

Patent

active

050596063

ABSTRACT:
A combination intended to induce and stimulate hair growth and reduce hair loss comprising a first component containing at least one calcium antagonist in a physiologically acceptable medium and a second component containing, in a physiologically acceptable medium, at least one pyrimidine derivative having the formula: ##STR1## In formula (I) R.sub.1 represents the group ##STR2## in which R.sub.3 and R.sub.4 are independent of each other and represent hydrogen, an alkyl, alkenyl, alkylaryl or cycloalkyl group, or R.sub.3 and R.sub.4 form a heterocycle with the nitrogen atom joined thereto, and represent an aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, hexahydroazepinyl, heptamethyleneimine,

REFERENCES:
patent: 4139619 (1979-02-01), Chidsey
patent: 4820512 (1989-04-01), Grollier

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