Biological and analytical uses of phenalenone and benzphenalenon

Details Biological and analytical uses of phenalenone and benzphenalenon Biological and analytical uses of phenalenone and benzphenalenon

1986-01-31

1989-02-07

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 4, 436546, 436800, 436805, 564426, 564427, 568 63, 568326, C12Q 102

Patent

active

048031615

ABSTRACT:
Certain phenalenone and benzphenalenone fluorescent compounds are useful in biomedical studies and analytical determinations. These compounds are particularly useful in assays for living organisms, e.g. microorganisms, carried out at a pH of 9 or less. For these determinations, the compounds can be attached to reducible compounds which will subsequently release the fluorescent moiety upon reduction. In the presence of an electron transfer agent, the reducible compounds are easily reduced by a microorganism.

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Kuznetsova et al.-Chem. Abst., vol. 96, (1982), p. 217,019e.
Solodar et al.--Chem. Abst., vol. 94 (1981), p. 3873p.
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Wolfbeis et al., Bull. Chem. Soc. Japan, 58, pp. 731-734 (1985).
Koller et al., Anal. Biochem. 143, pp. 146-151 (1984).
Cooke et al., Austral. J. Chem. 11, pp. 230-235 (1958).
Solodar et al., Zhurnal Organicheskoi Khinii, 16, (5), pp. 1062-1064 (1980).

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