Peptide-beta-lactamase conjugates for enzyme-linked immunoassays

Details Peptide-beta-lactamase conjugates for enzyme-linked immunoassays Peptide-beta-lactamase conjugates for enzyme-linked immunoassays

1985-09-11

1989-02-07

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 18, 435 19, G01N 3353

Patent

active

048031569

ABSTRACT:
A reagent for an ELISA determination of an antibody, the reagent comprising a peptide covalently linked to beta-lactamase. The reagent can be used in the following method to detect antibodies in a sample which involves

REFERENCES:
Yolken et al., "The Use of Beta-Lactamase in Enzyme Immunoassays for Detection of Microbial Antigens", Journal of Immunological Methods, 73, 109-123 (1984).
Neurath et al., "Radioimmunoassay and Enzyme-Linked Immunoassay of Antibodies . . . ", Journal of Virological Methods, 11, 75-86 (1984).
Borkar et al.--Chem. Abst., vol. 102 (1985) p. 198721b.
Yolken et al.--J. Clin. Microbiol., vol. 19, No. 3 (1984) pp. 356-360.
Villa-Komaroff et al.--Chem. Abst., vol. 89 (1978) p. 159988n.
Joshi et al.--Chem. Abst., vol. 91 (1979) p. 153815y.

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