Process for obtaining a factor XIII preparation, and its use

Details Process for obtaining a factor XIII preparation, and its use Process for obtaining a factor XIII preparation, and its use

1985-05-23

1986-07-01

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

424101, 424105, 514 2, 514 8, 514 21, 530851, 530416, C07K 320, C07K 322, C07K 324, A61K 3548

Patent

active

045978999

ABSTRACT:
A process for obtaining a factor XIII preparation is described, in which the factor XIII is precipitated from a placental extract using an alcohol, and is adsorbed onto an anion exchanger, and the exchanger is washed and the factor XIII is eluted. The factor XIII preparation obtained can be used for the treatment of disturbances of blood coagulation.

REFERENCES:
patent: 3310471 (1967-03-01), Parcells
patent: 3409605 (1968-11-01), Florini
patent: 3904751 (1975-09-01), Zwisler et al.
patent: 3931399 (1976-01-01), Bohn et al.
patent: 4285933 (1981-08-01), Fukushima et al.
patent: 4327086 (1982-04-01), Fukushima et al.

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