Polypeptide with 46 Kdalton HMFG differentiation antigen binding

Details Polypeptide with 46 Kdalton HMFG differentiation antigen binding Polypeptide with 46 Kdalton HMFG differentiation antigen binding

1990-11-01

1995-10-03

Fleisher, Mindy B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4241841, 435 71, 530350, C07K 1300, A61K 3900, C12Q 100

Patent

active

054550319

ABSTRACT:
A polypeptide has the antibody binding activity of the 46K dalton HMFG differentiation antigen and/or homology to at least one of the light chains of clotting factors V and VIII and is also provided as a fusion protein with a second antigenic polypeptide. An antibody has affinity for the polypeptide of the invention or a functional fragment thereof. in vivo and in vitro methods for therapy vaccination and detecting the presence of the polypeptide, the antibody, the DNA and RNA of the invention are provided. DNA and RNA sequences encode the polypeptide of the invention or fragments thereof and immunoassay kits comprise the antibodies and/or polypeptides of the invention.

REFERENCES:
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