Spiro lactam dual action inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540527, 540524, 540488, 540490, 540523, 540492, 540500, 544 54, 544 47, 544 90, 546138, 514211, 5142272, 514306, 5142268, 5142305, 514221, 514218, A61K 3155, C07D40312, C07D40314, C07D22312

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active

056542941

ABSTRACT:
Compounds of the formula ##STR1## are disclosed as possessing inhibotory activity against angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) and thus being useful as cardiovascular agents. Processes for preparing these compounds are also disclosed.

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