Nucleotides for topical treatment of psoriasis, and methods for

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 48, 514 51, 514256, 514261, 514269, 514861, 514863, 514887, 536 2626, 536 267, 536 268, 544242, 544264, A61K 31505, A61K 3152, A61K 3170

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056542860

ABSTRACT:
Typical treatment of psoriasis and other diseases of skin cell hyperproliferation using pharmaceutical compositions containing mono-, di, and tri-phosphate esters of antiproliferative nucleoside analogs and related analogs, DNA chain-terminating dideoxynucleosides and other nucleoside analogs. The useful phosphate esters include phosphoramidates and phosphothiorates, as well as polyphosphates having C and S bridging atoms.

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