Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-05-19
2000-09-19
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514241, 51425201, 51425204, 51425205, A61K 314965, A61K 31497
Patent
active
061212660
ABSTRACT:
Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R.sub.1 is a halogen, or an oxygen linked leaving group including an aromatic ether, an alkyl sulfonate, an aryl sulfonate, an alkyl phosphonate, an aryl phosphonate, an alkyl phosphate or aryl phosphate;
REFERENCES:
patent: 4215109 (1980-07-01), Ruhenstroth-Bauer et al.
patent: 4590194 (1986-05-01), Lesher et al.
patent: 4710499 (1987-12-01), Wermuth et al.
patent: 5055451 (1991-10-01), Krantz et al.
patent: 5081145 (1992-01-01), Guindon et al.
patent: 5418233 (1995-05-01), Linz et al.
Alfred Dornow et al., "Synthesen von Pyrazolo[3.4-c]pyridazinen", Chemische Berichte, 97(12), pp. 3349-3353 (1964).
HCAPLUS abstract, AN 1993:625966, Linz, G. et al., abstract of EP 537696 A1, Apr. 21, 1993.
Wermuth et al., J. Med. Chem., 32, pp. 528-537. (1989).
Ator Mark A.
Dolle Roland E.
Hoyer Denton W.
Rinker James M.
Ross Tina Morgan
Dixon Lisa A.
Haley, Jr. James F.
Raymond Richard L.
Vertex Pharmaceuticals Inc.
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