Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-05-29
2000-01-04
Johnson, Nancy A
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 914, 435 915, 435 691, 4353201, 435325, 536 231, 536 234, 536 235, C12Q 168, C07H 2104, C12P 1934, C12N 1585
Patent
active
060108533
ABSTRACT:
The invention provides isolated nucleic acids molecules, designated Siva nucleic acid molecules, which encode proteins involved in immune cell apoptosis. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing Siva nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a Siva gene has been introduced or disrupted. The invention still further provides isolated Siva proteins, fusion proteins, antigenic peptides and anti-Siva antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
REFERENCES:
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GenBank.RTM. Access
Ao Zhaohui
Kanteti Prasad V. S.
Schlossman Stuart F.
Bansal Geetha P.
Dana-Farber Cancer Institute
Johnson Nancy A
Mandragouras, Esq. Amy E.
Williams, Ph.D. Megan E.
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