Interleukin-1.beta. converting enzyme like apoptosis protease-10

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352523, 43525411, 4353201, 435325, 435455, 435471, 514 44, 536 231, 536 235, C12N 1512, C12N 1563, C12N 115, C12N 121, C07H 2100

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061210188

ABSTRACT:
ICE-LAP-10 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ICE-LAP-10 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

REFERENCES:
Orkin et al., "Report and recommendations of the panel to assess the NIH investment in research on gene therapy", issued by the U.S. National Institutes of Health, Dec. 1995.
Ngo et al., "Computational complexity, protein structure prediction, and the Levinthal paradox", in `The Protein Folding Problem and Tertiary Structure Prediction`, Merz et al. (eds.), Birkhauser Boston: Boston, MA, pp. 433 & 492-495, 1994.
Munday et al., "Molecular Cloning and Pro-apoptotic Activity of ICE .sub.re1 II and ICE .sub.re1 III, Members of the ICE/CED-3 Family of Cysteine Proteases", The Journal of Biological Chemistry, 270(26) pp. 15870-15876 (1995).
Faucheu et al. "A Novel Human Protease Similar To The Interleukin-1.beta. Converting Enzyme Induces Apoptosis in Transfected Cells", The EMBO Journal, 14(9) , 1914-1922 (1995).
Kamens et al., "Identification and Characterization of ICH-2, a Novel Member of the Interleukin-1.beta.-converting Enzyme Family of Cysteins Proteases", The Journal of Biological Chemistry, 270(25), pp. 15250-15256 (1995).
Accession No. U28014, Sep. 6, 1995, Munday, et al., "Molecular Cloning and Pro-apoptotic Activity of ICE.sub.rel III, and Members of the ICE/CED-3 Family Cysteine Proteases".
Accession No. U25804, Feb. 7, 1996, Kamens, et al., "Identification and Characterization of ICH-2, a Novel Member of the Interluekin-1 Beta-Converting Enzyme Family of cysteine Proteases".
Accession No. Z48810, Nov. 10, 1995, Faucheu, et al., "A Novel Human Protease Similar to the Interleukin-1 Beta Converting Enzyme Induces Apoptosis in Transfected Cells".
Accession No. U28015, Sep. 6, 1995, Munday, et al., "Molecular Cloning and Pro-apoptotic Activity of ICE.sub.re1 II and ICE.sub.re1 III, Members of the ICE/CED-3 Family Cysteine Proteases".

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