Preparation of fibrous collagen product having hemostatic and wo

Details Preparation of fibrous collagen product having hemostatic and wo Preparation of fibrous collagen product having hemostatic and wo

1978-04-18

1979-04-10

Morris, Theodore

Compositions: coating or plastic

Coating or plastic compositions

Proteinaceous material containing

C08L 8900, C09H 100

Patent

active

041486641

ABSTRACT:
A fluffy, finely-divided fibrous collagen derived product having hemostatic and adhesive properties sufficient to join together severed biological surfaces in a live warm blooded animal when the product is wet with blood between the surfaces. In the preparation of the product, water-wet collagen is treated with ethanol to remove water, is converted to a ionizable partial salt in the presence of ethanol and dehydrated with ethanol so as to control and limit the swelling of the collagen fibers and prevent hornification upon drying. The recovered dry material is subjected to deaggregation to form a mass having a bulk density of not more than 8 pounds per cubic foot and a surface area of at least 1 square meter per gram.

REFERENCES:
patent: 2928822 (1960-03-01), Johnson et al.
patent: 3628974 (1971-12-01), Battista

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