Methods for detecting bcl-3 gene in human leukemias

Details Methods for detecting bcl-3 gene in human leukemias Methods for detecting bcl-3 gene in human leukemias

1989-11-15

1992-09-22

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 5, 435 723, 4351223, 436501, 436538, 436813, 536 27, 935 19, 935 2, C12Q 168, C12Q 1500, G01N 33566, C07H 1512

Patent

active

051496283

ABSTRACT:
Bcl-3 gene sequences can be used to monitor the success of chemotherapy and to detect minimal residual disease in patients having hematopoietic malignancies. Bcl-3 sequences can also be used to identify new cellular oncogenes involved in hematopoietic cell malignancies by taking advantage of their adjacency to the bcl-3 promoter. Particular nucleic acid probes and primers are also provided by the disclosure.

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