Topically applied clotting material

Details Topically applied clotting material Topically applied clotting material

1999-02-08

2000-05-09

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 57, 514 58, 514 60, A61K 31715

Patent

active

060604611

ABSTRACT:
A composition, system, articles and method for the enhancement of clotting in wounds with extravascular blood flow, especially where the surface of the tissue has been broken is described. The system consists of biotolerable, porous particulates applied to the surface of a wound with liquid blood thereon. The porous nature of the particulate material, either free-flowing or packaged or restrained on or in a surface, enhances clotting. Chemical or biochemical agents, such as additional clotting agents, therapeutic agents, antibiotics, clot strengthening agents (such as fibrous structural materials), and the like may optionally be included on, with or within the porous particles. The particles may comprise such diverse materials as organics, metallics, inorganics, ceramics, and the like, both natural and artificial. It is generally preferred that the pore size distribution lies within a general range, and this range may vary from animal to animal and condition to condition, but generally falls within about 0.5 to 1000 nanometers or 3,000 to 200,000 Daltons.

REFERENCES:
patent: 4188390 (1980-02-01), Campbell
patent: 4317729 (1982-03-01), Yamashita et al.
patent: 4344949 (1982-08-01), Hoefle et al.
patent: 4373519 (1983-02-01), Errede et al.
patent: 4482514 (1984-11-01), Schindler et al.
patent: 4740594 (1988-04-01), Mauzac et al.
patent: 4743450 (1988-05-01), Harris et al.
patent: 5348941 (1994-09-01), Middaugh et al.
patent: 5529929 (1996-06-01), Rossi, Jr. et al.
patent: 5593729 (1997-01-01), Frechet et al.
patent: 5624612 (1997-04-01), Sewall et al.
patent: 5675006 (1997-10-01), Karimian et al.
patent: 5686612 (1997-11-01), Karimian et al.
patent: 5700902 (1997-12-01), Hancock et al.
patent: 5817381 (1998-10-01), Chen et al.
Associated Press, "FDA approves glue to replace some stitches", The Augusta Chronicle, http://augustachronicle.com/stories/082898/tec.sub.- 124-8747.shtml.BAK1, 1-2, (Aug. 27, 1998).
Dr. Christopher, "Abrasions", Dr. Christopher Enterprises, http://www.drchristopher.com/ail/abrasio3.htm, 1-2, (1998).
Encyclopedia, "Anticoagulant", The Columbia Encyclopedia, Fifth Edition, Columbia University Press, http://www.infoplease.com/ce5/CE002395.html, 1, (1993).
McCall, W., "Lasers, elastin patch could stem bleeding on battlefields", The Detroit News, http://detnews.com/96/discover/9701/05/12300058/htm, 1-2, (Dec. 30, 1996).
Merritt, T.B., "Help!My Bird is Bleeding", Winged Wisdom Pet Bird Magazine, Ezine, Article V http://www.birdsnways.com/wisdom/ww17ev.htm, 1-2, Nov. 1997).
Thermogenesis, "Asahi Medical to Begin Initial Human Clinical Studies in Japan of the ThermoGenesis CryoSeal System Pre-Clinical Study Validates Clotting Adhesive and Wound-Healing Protein Levels in Cryoprecipated AHF Produced by CryoSeal System", ThermoGenesis Press Release, http://www.thermogenesis.com/pressreleases/preclinic.html, 1-2, (Aug. 1997).
Warkentin, T.E., "Recent Advancements in the Mangement of Heparin-Induced Thrombocytopenia", Thrombosite Nwsletter, vol. 1, Iss. 1, http://www.thrombosite.com/tsnews/tsnews1.sub.- 1.html, 1-16, (Mar. 1998).

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