Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-06-05
1988-05-24
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544309, 544310, 544311, 544312, 544317, 544318, A61K 31495, C07D23947, C07D23954, C07D23956
Patent
active
047466642
ABSTRACT:
New pyrimidine derivatives of the formula: ##STR1## wherein Z is a group selected from ##STR2## in which R.sup.1 and R.sup.2 are each hydrogen, alkenyl, ar(lower)alkyl or lower alkyl optionally substituted with epoxy, hydroxy, amino and/or lower alkylamino and R.sup.5 is lower alkyl,
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Taguchi et al, CA91-211365q and J. Org. Chem. 1979, 44(24), 4385-93.
Taguchi et al, CA 88-5875r and J. Org. Chem. 1977, 42(25), 4127-31.
Maehr et al. CA78-147903r and J. Heterocyclic Chem. 1972, 9(6), 1389-94.
Ekpenyong et al. CA89-197441m and Tetrahedron Lett. 1978(19), 1619-22.
Johnson et al, JACS. vol. 37(1915), pp. 378-383.
Ito Kiyotaka
Murata Masayoshi
Takaya Takao
Fujisawa Pharmaceutical Co. Ltd.
Gerstl Robert
Shen Cecilia
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