Substituted oxotremorine derivatives

Details Substituted oxotremorine derivatives Substituted oxotremorine derivatives

1995-02-22

1996-08-27

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514422, C07D40312, A61K 3140

Patent

active

055502571

ABSTRACT:
This disclosure describes novel substituted oxotremorine derivatives of formula I having nitrogen, oxygen or sulfur groups and the prodrug forms of these derivatives. The compounds have cholinergic activity. Also disclosed are methods for treating diseases of the central nervous system in mammals employing the compounds, pharmaceutical preparations containing the compounds and the processes for the production of the compounds. ##STR1##

REFERENCES:
patent: 3920824 (1975-11-01), Rajadhyaksha
patent: 4065471 (1977-12-01), Dickinson
patent: 4833139 (1989-05-01), Martin
patent: 4937235 (1990-06-01), Trybulski
Levy et al., Therapie, 22 (3): 671-688 (Jan. 1967).
Ehlert et al., Mol. Pharmacology, 28: 107-119 (1985).
Ringdahl, Eur. J. Pharmacol., 99: 177-184 (1984).
Ringhdahl, The Humana Press, Clifton, NJ, J. H. Brown, Ed., 1989, 151.
Lundkvist et al., J. Med. Chem., 32, 863-869 (1989).
Resul et al., Acta. Pharm. Suec., 16, 13, pp. 161-165 (1979).

Affiliated with

Also associated with

Rating

Substituted oxotremorine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted oxotremorine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted oxotremorine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1057113