System and method for providing hemodynamically optimal pacing t

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

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607 25, A61N 1365

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active

055496504

ABSTRACT:
A system and method for a pacemaker are provided, for using cardiac wall motion sensor signals to provide hemodynamically optimal pacing therapy to patient at rest, and for providing rate-responsive pacing therapy. The cardiac wall motion sensor signals are provided by an implantable lead that incorporates an accelerometer for measuring cardiac mechanical activity. The cardiac wall motion sensor signals are processed to derive cardiac wall velocity signals and cardiac wall displacement signals. The derived signals are further processed to derive physiologic parameters indicative of cardiac performance, including stroke volume, contractility, pre-ejection period, and ejection time. The physiological parameters, in turn, are used by the pacemaker to provide hemodynamically optimal pacing therapy at rest, and rate-responsive pacing therapy.

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I. Ovsyshcher et al., "First Derivative of Right Ventricular Pressure dP/dt, as a Sensor for a Rate Adaptive VVI Pacemaker: Initial Experience," Pace, vol. 15, Feb. 1992, pp. 211-218.

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