Radiant energy – Ionic separation or analysis – Methods
Patent
1995-03-20
1996-08-13
Berman, Jack I.
Radiant energy
Ionic separation or analysis
Methods
2502521, 364498, 36457102, H01J 4900
Patent
active
055458955
ABSTRACT:
A method of correcting for instrumental changes that influence the spectral response of a mass spectrometer over time. The method entails determining and applying a transfer function which equalizes instrument bias between mass spectrometers and within the same mass spectrometer over time. A transfer function is specific to a particular mass spectrometer, and is based on the relationship between a reference spectrum of a standard as stored in a library and a spectrum of the standard obtained on the particular mass spectrometer of interest. This method facilitates and simplifies recalibration, provides enhanced library searching capabilities for mass spectrometry, and may permit concentration determination from mass spectral data without the need to recalibrate an instrument with multiple standards.
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Beebe Kenneth R.
Blaser Wayne W.
LaPack Mark A.
Leugers Mary A.
Wright Larry G.
Berman Jack I.
Meier Linda Blair
The Dow Chemical Company
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