Lipoxygenase-inhibiting compounds derived from non-steroidal ant

Details Lipoxygenase-inhibiting compounds derived from non-steroidal ant Lipoxygenase-inhibiting compounds derived from non-steroidal ant

1990-04-19

1993-06-15

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Hydroxamic acids, chalcogen analogs or salts thereof

560 24, 558232, 564 26, 564 56, C07D 8308, C07D 8310, A61K 31325

Patent

active

052200590

ABSTRACT:
Compounds of the formula: ##STR1## wherein R.sub.1 is selected from (1) hydrogen; (2) --NR.sub.2 R.sub.3, --OR.sub.2 or --SR.sub.2 where R.sub.2 and R.sub.3 are independently selected from hydrogen, alkyl, aryl and alkylaryl; and (3) optionally substituted C1-C8 alkyl, C2-C8 alkenyl, arylalkyl or cycloalkyl;

REFERENCES:
patent: 3388153 (1968-06-01), Johnson
patent: 4156739 (1979-05-01), Fountain et al.
patent: 4412994 (1983-11-01), Sloan et al.
patent: 4760057 (1988-07-01), Alexander
patent: 4874759 (1989-10-01), Tahara et al.
patent: 5026729 (1991-06-01), Brooks et al.

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