Process for preparing highly substituted phenyls

Details Process for preparing highly substituted phenyls Process for preparing highly substituted phenyls

1990-02-15

1991-12-10

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 71, 560 59, C07C 6988

Patent

active

050720236

ABSTRACT:
A process is described in which a lactone ##STR1## is reacted with an alkylester X.sup.1 --CH.sub.2 and an oxidizing or dehydrogenating agent to form the phenol ester ##STR2##

REFERENCES:
F. M. Hauser et al., "A New Procedure for Regiospecific Syntheses of Benzopyran-1-One", J. Org. Chem. 53 (1988), 4676-4681.
F. M. Hauser et al., "Syntheses of .alpha.-and .beta.- Sorigenin Methyl Esters", J. Org. Chem. 42 (1977), 4155-4157.
A. M. Echavarren et al., "Palladium-Catalyzed Coupling of Aryl Triflates with Organostannes", J. Am. Chem. Soc. 109 (1987), 5478-5486.
F. M. Hauser et al., "Preparation of Ethyl 1-Hydroxy-2-Naphthoates from 1H.gtoreq.2-Benzopyran-1-Ones: A New Method", J. Heterocyclic Chem. 15 (1978), 1535.
R. A. Abramovitch et al., "New Methods of Arylation", Tetrahedron 44 (1988), 3039.
O. Toussaint et al., "The Copper (I)-Catalyzed Decarboxylation of Malonic Acids: A New Mild and Quantitative Method", Synthesis (1986), 1029.
P. Brownbridge, "Silyl Enol Ethers in Synthesis-Part I", Synthesis (1983), 1-28.
P. Brownbridge, "Silyl Enol Ethers in Synthesis-Part II", Synthesis, (1983) 85-104.
G. E. Stokker et al., "3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors. 1. Structural Modification of etc. . .", J. Med. Chem. 28 (1985), 347-358.
A. P. Krapcho et al., "Synthetic Applications and Mechanism Studies of the Decarbalkoxylations of Geminal Diesters and Related Systems Effected in Me.sub.2 SO by Water and/or etc. . .", J. Org. Chem. 43 (1978), 138-147.
G. E. Stokker et al., "3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors. 3. 7-(3,5-Disubstituted)1,1' etc. . .", J. Med. Chem. 29 (1986), 170-181.
W. F. Hoffman et al., "3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors. 2. Structural Modification of etc. . .", Journal of Medicinal Chemistry 2 (1986), 159-169.
G. E. Stokker et al., "3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors. 5. 6-(Fluoren-9-yl)- and 6-(Fluoren etc. . .", Journal of Medicinal Chemistry 29 (1986), 852-855.

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