2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-male

Details 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-male 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-male

1981-09-02

1984-11-06

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546307, 546308, C07D21375, A61K 3144

Patent

active

044812051

ABSTRACT:
There is prepared 2-amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate of the formula ##STR1## The compound has antiphlogistic and analgesic properties in the same manner as the known hydrochloride salt. In contrast to the hydrochloride 2-amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate can be produced without a disturbing blue coloration. This maleate generally is formed from a mixture of two crystal modifications A and B, whereby there is especial advantageous in regard to isolation as well as the galenical preparations a mixture entriched in modification A (60 to 90% modification A).

REFERENCES:
patent: 3969361 (1976-07-01), von Bebenburg et al.

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