Recombinant human and rat protein kinase C polypetides

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 691, 536 232, C12N 912, C12N 1554

Patent

active

052197484

ABSTRACT:
Human protein kinase C and rat protein kinase C, recombinant DNA containing DNA sequence coding for kinase C, a transformant transformed with a vector containing the above recombinant DNA, and the production method of human or rat kinase C by cultivating the transformant are disclosed.
Kinase C is useful as reagent for studying cellular signal transduction mechanism, as diagnostic and inspection agent for disease, for example tumor, resulting from the trouble of cellular signal transduction mechanism, and as screening agent for a preventive agent or medicine to the disease.

REFERENCES:
Knopf et al. (1986) Cell 46:491-502.
Suggs, S. V., et al., 1981, Proceedings, National Academy of Sciences, USA 78: 6613-6617.
Kikkawa, U., et al., 1986, Biochemical and Biophysical Research Communications, 135: 636-643.
Kikkawa, U., et al., 1983, Methods in Enzymology 99: 288-298.
Ballester, R., et al., 1985, Journal of Biological Chemistry 260:15194-15199.
Ohno, S., 1989, Biotrend (Tokyo), 1-2: 22-27.
Ono, Y., 1991, in, Gan Idenshi Keakyu, Saikin No Shimpo, Igakush, C., Ed., at pp. 138-145.
Housey, et al., Journal of Cellular Biochemistry, Suppl. 10C (1986).
Ullrich, et al., Cold Spring Harbor Symposia on Quantitative Biology, vol. L1:713 (1986).
Ono, et al., FEBS Letters, vol. 203:111 (1986).
Makowske et al., The Journal of Biological Chemistry, vol. 261:13389 (1986).
Ono et al., FEBS Letters, vol. 206:347 (1986).
Housey et al., PNAS, vol. 84:1065 (1987).
Ono et al., Science, vol. 236:1116 (1987).
Kikkawa et al., FEBS Letters, vol. 217:227 (1987).
Coussens et al., DNA, vol. 6:389 (1987).
Nishizuka et al., Science, vol. 233:305 (1986).
Nishizuka, "The Role of Protein Kinase C in Cell Surface Signal transduction and Tumour Promotion", Nature 308: 693 (1984).
Nishizuka, "Studies and Perspectives of Protein Kinase C", Science 233: 305 (1986).
Parker et al., "The Complete Primary Structure of Protein Kinase C-The Major Phorbol Ester Receptor", Science 233: 853 (1986).
Coussens et al., "Multiple, Distinct Forms of Borine and Human Protein Kinase C etc.", Science 233: 859 (1986).
Knopf, et al. "Cloning and Expression of Multiple Protein Kinase C cDNAs", Cell 46: 491 (1986).
Ohno et al., "Tissue-Specific expression of Three Distinct Types of Rabbit Protein Kinase C", Nature 325: 161 (1978).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Recombinant human and rat protein kinase C polypetides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant human and rat protein kinase C polypetides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant human and rat protein kinase C polypetides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1041987

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.