Substituted basic 2-aminotetralin in pharmaceuticals

Details Substituted basic 2-aminotetralin in pharmaceuticals Substituted basic 2-aminotetralin in pharmaceuticals

1989-07-12

1991-06-25

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514305, 514255, 514431, 514432, 514447, 514430, 514450, 514459, 514471, 546206, 546133, 540484, 544398, 544395, 548542, 548557, 548950, 549346, 549424, 549449, 549510, 549 9, 549 13, 549 68, A61K 31445, C07D21158

Patent

active

050268570

ABSTRACT:
For treatment of disorders of the central nervous system, the cardiovascular system or the intestinal tract, the new substituted basic 2-aminotetralins of the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl,

REFERENCES:
patent: 4707497 (1987-11-01), Cecchi et al.
Christova et al., CA 94: 30049t, CA 90: 87114t.
Uvanov et al., CA 88: 89624u.
Chemical Abstracts, vol. 106, Feb. 2, 1987, No. 5, p. 94, 106: 28103s, Emerit et al., "Irreversible blockade of central 5-HT1A receptor . . .".

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