Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-02-28
1991-12-10
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3140
Patent
active
050718673
ABSTRACT:
A method of healing extracellular matrix degradation to reverse glomerular sclerosis includes the steps of administering on angiotension I converting enzyme inhibitor and suppressing extracellular matrix release independent of the blood pressure effects of the enzyme inhibitor.
REFERENCES:
Kidney Int. 32:794-800, 1987, Beukers et al.
Kidney Int. 36:626-635, 1989, Yoshida et al.
Kidney Int. 36:969-977, 1989, Brunner et al.
J. Clinical Invest. 85:541-549, Feb. 1990, Remuzzi et al.
Fogo Agnes
Ichikawa Iekuni
Ikoma Masaaki
Kawamura Tetsuya
Friedman Stanley J.
Vanderbilt University
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