Benzoxazepine derivative

Details Benzoxazepine derivative Benzoxazepine derivative

1989-12-21

1991-12-10

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540490, A61K 3153, C07D52100

Patent

active

050718452

ABSTRACT:
A benzoxazepine derivative suitable for use as a psychotropic composition having the formula: ##STR1## wherein A and B are both carbonyl groups, or one thereof represents a methylene group and the other a carbonyl group, R represents an aromatic group or a heterocyclic group, which may be substituted, X represents a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.5 lower alkyl group, a C.sub.1 -c.sub.5 lower alkoxy group, a C.sub.7 -C.sub.9 arylalkoxy group, a hydroxyl group, a nitro group, or an ester group, and n is an integer of 2 to 10 and salts thereof.

REFERENCES:
patent: 3738999 (1973-06-01), Krapcho et al.
patent: 3794639 (1974-02-01), Krapcho et al.
patent: 4386090 (1983-05-01), Moinet et al.
patent: 4431851 (1984-02-01), Moinet et al.
patent: 4504663 (1985-03-01), Moinet et al.
Huckle et al., "The Preparation of Some 2,3-Dihydro-1,4-Benzoxazepin-5(4H)-ones and Related Compounds", Journal of the Chemical Society (Feb. 1965, pp. 1137-1141.

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