Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-08-29
1979-05-22
Schwartz, Gerald A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
560 21, 260566F, 1951035R, C07C11900
Patent
active
041559169
ABSTRACT:
Analysis of proteinases is accomplished using conventional amino acid containing aromatic amine substrates. Aromatic amines such as 4-methoxy-2-naphthylamine (4M2NA), 2-naphthylamine, aminoisophthalic acid dimethyl ester, p-nitroaniline, 5-methoxy-1-aminofluorene and coumarin derivatives resulting from enzymatic hydrolysis of the substrate couples with aromatic aldehydes such as 5-nitrosalicylaldehyde (5-NSA), benzaldehyde and p-nitrobenzaldehyde to produce Schiff-base complexes which are water insoluble. Certain Schiff-base complexes produce a shift from blue to orange-red (visible) fluorescence. Such complexes are useful in the assay of enzymes.
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Dolbeare Frank A.
Smith Robert E.
Figg Edward A.
McNett John C.
Schwartz Gerald A.
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