Use of 5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-ones s

Details Use of 5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-ones s Use of 5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-ones s

1989-06-15

1991-06-25

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 3155

Patent

active

050266993

ABSTRACT:
5,11-Dihydro-6H-pyrido[2,3-b][1,4]-benzo-diazepinones substituted in the 11-position corresponding to general formula I ##STR1## wherein R.sup.1 and R.sup.2 represent hydrogen atoms or alkyl groups having 1 to 3 carbon atoms, A.sup.1 is a straight-chained or branched alkylene group with 1 to 5 carbon atoms, A.sup.2 is a methylene group or, if R.sup.1 is hydrogen and R.sup.2 is methyl, A.sup.2 may also be an ethylene group, and the physiologically acceptable acid addition salts thereof are suitable for treating bradycardia and bradyarrhythmia and spasm in the colon, bladder and bronchi.

REFERENCES:
patent: 3660380 (1972-05-01), Schmidt et al.
patent: 4210648 (1980-07-01), Schmidt et al.
patent: 4424222 (1984-01-01), Engel et al.
patent: 4550107 (1985-10-01), Engel et al.
patent: 4873236 (1989-10-01), Engel et al.
Thomas, Chem. Abs., vol. 90, No. 17, entry #137875s (1979).

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