Novel AZT analogs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514885, 536 23, A61K 3170

Patent

active

050266888

ABSTRACT:
The present invention relates to novel ester derivatives of the anti-retroviral compound AZT, and compositions containing same. It also relates to methods of treatment of retroviral infections comprising administration of said compounds to individuals in need of such treatment.

REFERENCES:
Weiss et al., Molecular Biology of Tumor Viruses, 2nd Edition, Cold Spring Harbor Laboratory, (1984), pp. 46-51.
Torrence et al. "AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become locked in the central nervous system." FEBS Letters, 1988 (Jul.), vol. 234(1), 135-140.

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