Inhibitors of mammalian collagenase

Details Inhibitors of mammalian collagenase Inhibitors of mammalian collagenase

1982-09-24

1984-01-03

Phillips, Delbert R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424177, 424256, 424274, 424311, 424317, 424326, 562556, 544162, 548566, 546246, 564152, 560153, C07D21126, C07D23902, C07D26530, A61K 3700, C01G 4300, C01B 1516, C01B 2516, C01B 3320, C07C14920, C07C14702

Patent

active

044243545

ABSTRACT:
Mammalian collagenase is inhibited by compounds of the formula ##STR1## or salts thereof, wherein R is hydrogen, alkanoyl of 2 to 10 carbon atoms or arylcarbonyl;

REFERENCES:
patent: 4235885 (1980-11-01), Sundeen et al.
patent: 4382081 (1983-05-01), Sundeen et al.
"Structure-Inhibition Relationships Among Metal-Binding Collagen Peptide Analogues" Hussain Saneii and Arno F. Spatola (Spon: John W. Brown) University of Louisville, Ky., 40292, May 1, 1981, vol. 40, No. 6.

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