Wound-healing dressings and methods

Details Wound-healing dressings and methods Wound-healing dressings and methods

1988-06-21

1990-11-27

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424428, 424429, 514 2, 514 21, 514953, 514954, 514944, A61K 970, A61K 3702

Patent

active

049734660

ABSTRACT:
Wound healing dressings are prepared by flocculating fibronectin, a biologically active fragment or an analog thereof to produce a water-swellable gel. The gels, in the form of sheets, strips, wedges, strands or I-shaped cross-sections, are especially useful in promoting the healing of corneal, scleral dermal, incisional wounds or lesions. They can be used to enhance the results obtained in keratorefractive surgeries and the healing scleral incision for intraocular surgery.

REFERENCES:
patent: 4377572 (1983-03-01), Schwarz et al.
patent: 4453939 (1984-06-01), Zimmerman et al.
patent: 4683142 (1987-07-01), Zimmermann et al.
patent: 4727059 (1988-02-01), Binder et al.
patent: 4740498 (1988-04-01), Hirao et al.
patent: 4784989 (1988-11-01), Hook et al.
Caffesse et al., "The effect of citric acid and fibronectin application on healing . . . " BA 80(11):93485, 1985.
Nishida et al., "Fibronectin enhancement of corneal epithelial wound healing of rabbits in vivo" BA 78(2):15426, 1984.
Fujikawa et al., "Fibronectin in healing rabbit corneal wounds" BA 73(3):21245.

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